The purpose of the study was to explore the mechanism underlying the enhanced subthalamic we care vitamin a and d ointment nucleus (STN) neural activity during exhausting exercise from the perspective of monoamine neurotransmitters and changes of their corresponding receptors.Rats were randomly divided into microdialysis and immunohistochemistry st
A distal intergenic region controls pancreatic endocrine differentiation by acting as a transcriptional enhancer and as a polycomb response element.
Lineage-selective expression of developmental genes is dependent on the interplay between activating and repressive mechanisms.Gene activation is dependent on cell-specific transcription factors that recognize transcriptional enhancer sequences.Gene repression often depends on the recruitment of Polycomb group (PcG) proteins, although the sequences
First three new species of free-living marine nematodes of the Molgolaimus (Nematoda: Desmodoridae) from the continental shelf of the Brazilian coast (Atlantic Ocean)
Three new species of the Molgolaimus (Nematoda: Desmodoridae) are described from sample sediments collected in the South Atlantic, along the continental shelf break of Northeastern Brazil.This is the first time that new species of Molgolaimus have been described from sample sediments collected in the Brazilian coast.Molgolaimus sigmoides sp.nov.is
Distributed cognition and process management enabling individualized translational research: The NIH Undiagnosed Diseases Program experience
The National Institutes of Health Undiagnosed Diseases Program (NIH UDP) applies translational dosatron d40mz2 research systematically to diagnose patients with undiagnosed diseases.The challenge is to implement an information system enabling scalable translational research.The authors hypothesized that similarly complex problems are resolvable thr